|Name:||Gene Ontology Top Level|
|Also Known As:|
|Intent:||To represent types of gene-related entities and their parts.|
|Reusable OWL Building Block:||http://www.ontologydesignpatterns.org/cp/owl/gotop.owl (48)|
|Consequences:|| It allows to categorize gene-related types into three main types.
It allows to represent parts of gene-related entities (transitively). It does not allow to represent the relationships between entities of different types. It does not say anything about disjointness of categories.
|Scenarios:||A 'template for synthesis of G-rich strand of telomere DNA activity' must be part of a 'telomerase activity', All 'templates for synthesis of G-rich strand of telomere DNA activity' are 'molecular functions'|
|Examples (OWL files):|
The GO Top Content OP locally defines the following ontology elements:
Cellular component (owl:Class) The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
Molecular function (owl:Class) Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
Biological process (owl:Class) Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
This pattern is peculiar to the biomolecular domain, where types of entities, rather than specific instances, are the main focus of interest. As a result, the Gene Ontology, based on this top-level categories, is a huge TBox. Part of can have this pattern as a specialization, if the three gene-related categories are considered as owl:subClassOf Entity.